The region is the whole ellipse \(\displaystyle \frac{x^{2}}{16}+\frac{y^{2}}{9}=1\), i.e. \(\displaystyle \frac{x^{2}}{4^{2}}+\frac{y^{2}}{3^{2}}=1\), so \(\displaystyle a=4\) along the \(\displaystyle x\)-axis and \(\displaystyle b=3\) along the \(\displaystyle y\)-axis.
The equation contains only \(\displaystyle x^{2}\) and \(\displaystyle y^{2}\), so the curve is symmetric about both axes. Hence the required area is four times the area of the part lying in the first quadrant.

In the first quadrant \(\displaystyle y\ge 0\), so solving the equation of the ellipse for \(\displaystyle y\),
\[\frac{y^{2}}{9}=1-\frac{x^{2}}{16}\quad\Rightarrow\quad y=\frac{3}{4}\sqrt{16-x^{2}},\qquad 0\le x\le 4 \]
Taking vertical strips of height \(\displaystyle y\) and width \(\displaystyle dx\) from \(\displaystyle x=0\) to \(\displaystyle x=4\),
\[\text{Area}=4\int_{0}^{4}y\,dx=4\int_{0}^{4}\frac{3}{4}\sqrt{16-x^{2}}\,dx=3\int_{0}^{4}\sqrt{16-x^{2}}\,dx \]
Applying the standard integral \(\displaystyle \int\sqrt{a^{2}-x^{2}}\,dx=\frac{x}{2}\sqrt{a^{2}-x^{2}}+\frac{a^{2}}{2}\sin^{-1}\frac{x}{a}+C\) with \(\displaystyle a=4\),
\[\text{Area}=3\left[\frac{x}{2}\sqrt{16-x^{2}}+8\sin^{-1}\frac{x}{4}\right]_{0}^{4} \]
At \(\displaystyle x=4\) the first term vanishes because \(\displaystyle \sqrt{16-16}=0\), and \(\displaystyle \sin^{-1}1=\frac{\pi}{2}\); at \(\displaystyle x=0\) both terms are \(\displaystyle 0\). So
\[\text{Area}=3\left[\left(0+8\cdot\frac{\pi}{2}\right)-0\right]=3(4\pi)=12\pi \]
(This agrees with the general formula \(\displaystyle \pi ab=\pi(4)(3)=12\pi\).)
The area of the region bounded by the ellipse is \(\displaystyle 12\pi\) square units.