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Biology · 2026 · 2 marks
Biotechnology and its ApplicationsBiotechnological Applications in Medicine2 marksUnderstandvery short answer
CBSE 2026 · Region 2 · Set 3 · Q18
A patent with Type I diabetes is unable to produce sufficient insulin. (a) How has recombinant DNA technology helped in addressing this problem? (b)…
A patent with Type I diabetes is unable to produce sufficient insulin.
(a)
How has recombinant DNA technology helped in addressing this problem ?
(b)
Mention its advantage over animal derived insulin.
Marking-scheme solution
(a)
Using recombinant DNA technology a company Eli Lily, prepared human
insulin in E.coli bacteria, in large quantity / By recombinant DNA technology a company Eli Lily prepared two DNA sequences corresponding to A and B chains of human insulin, introduced them in plasmids of E.coli, A and B chins produced separately are extracted and combined by creating disulfide bonds.
(b)
Animal derived insulin may cause allergy
whereas insulin produced by r DNA technology does not / Insulin produced by rDNA technology is produced in large quantity in comparison to animal derived insulin
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CBSE Class 12 Biology past-paper question from the 2026 board exam, with the answer as CBSE’s own marking scheme gives it. Where our answers come from.