(i) Nucleus
A dense, membrane bound organelle, first described by Robert Brown ($\displaystyle 1831$), that contains the chromatin and controls the activities of the cell.
It is bounded by a nuclear envelope of two parallel membranes with a space between them ($\displaystyle 10$ to $\displaystyle 50$ nm) called the perinuclear space; this forms a barrier between the contents of the nucleus and the cytoplasm.
The outer membrane usually remains continuous with the endoplasmic reticulum and bears ribosomes on it.
At a number of places the envelope is interrupted by nuclear pores, formed by the fusion of its two membranes; RNA and protein molecules move through them in both directions.
The nuclear matrix (nucleoplasm) contains the nucleolus and the chromatin. The interphase nucleus has highly extended nucleoprotein fibres (chromatin) containing DNA, histones, non-histone proteins and RNA.
The nucleoli are spherical, are not membrane bound (their content is continuous with the nucleoplasm), and are the site of active ribosomal RNA synthesis; they are larger and more numerous in cells actively making protein.
Diagram to draw: a large circle within which is drawn a double boundary line (the two membranes of the nuclear envelope) broken at two or three places by gaps; inside, a small dense sphere and a fine network of threads. Label: Nuclear membrane, Nuclear pore, Nucleoplasm, Nucleolus (and chromatin fibres). The book prints this as Figure $\displaystyle 8.11$.
(ii) Centrosome
An organelle usually containing two cylindrical structures called centrioles, surrounded by amorphous pericentriolar materials.
The two centrioles lie perpendicular to each other, and each has an organisation like a cartwheel.
Each centriole is made up of nine evenly spaced peripheral fibrils of tubulin protein, and each peripheral fibril is a triplet; the adjacent triplets are also linked.
The central part of the proximal region of the centriole is proteinaceous and is called the hub, which is connected to the tubules of the peripheral triplets by radial spokes made of protein.
Function: the centrioles form the basal body of cilia or flagella, and the spindle fibres that give rise to the spindle apparatus during cell division in animal cells.
Diagram to draw: show the two centrioles as two short cylinders set at right angles to each other, enclosed in a hazy zone. Beside them draw one centriole in transverse section as a cartwheel — a central hub, nine radial spokes running out from it, and at the end of each spoke a set of three linked tubules (a peripheral triplet fibril). Label: Centrioles, Pericentriolar material, Hub, Radial spoke, Peripheral triplet fibril. (The chapter prints a figure for the nucleus but not for the centrosome, so this one must be drawn from the description above.)
