If M_0 is the mass of isotope _5^12 B, M_p and M_n are the masses of proton and neutron, then nuclear binding energy of isotope is:

If $\displaystyle \mathrm{M}_0$ is the mass of isotope $\displaystyle { }_5^{12} \mathrm{~B}, \mathrm{M}_{\mathrm{p}}$ and $\displaystyle \mathrm{M}_{\mathrm{n}}$ are the masses of proton and neutron, then nuclear binding energy of isotope is :