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CBSE 2024 · Region 5 · Set 1 · Q31 · 5 marks

(i)
Draw a schematic diagram of the cloning vector pBR $\displaystyle 322$ and label ($\displaystyle 1$) Bam HI site ($\displaystyle 2$) gene for ampicillin resistance ($\displaystyle 3$) 'ori'
(4)
'rop' gene.
(ii)
State the role of 'rop' gene.
(iii)
A cloning vector does not have a selectable marker. How will it affect the process of cloning ?
(iv)
Why is insertional inactivation preferred over the use of selectable markers in cloning vectors ?

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